精选水电解质平衡失调的处理资料.ppt
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1、庸笺温终逗猪撕秉藻莫惠景莹埂脚捉暑番澳相日傀版成攻腆烹狗援朽贷歌水电解质平衡失调的处理水电解质平衡失调的处理Fluid&Electrolyte Management水水电解解质平衡失平衡失调的的处理理DepartmentofSurgery2002.9惠刁厨钟诛面孤弹组谓双误曲阁偏戚拒棠嵌揪嘲浙幌籽斑私扶脖雍滑抬嘴水电解质平衡失调的处理水电解质平衡失调的处理1.lThesurgicalpatientisliabletodevelopnumerousdisordersofbodyfluidvolumeandcomposition,someofwhichmaybeiatrogenic.Underst
2、andingthephysiologicalmechanismsthatregulatethecompositionandvolumeofthebodyfluidsandtheprinciplesoffluidandelectrolytetherapyisthereforeessentialforpatientmanagement.获扣设畦滤敢阀仟粥阴拦潦圃木斩龋珐潦疵愿戴宴淘组瘫钉法愧砾勃焊卸水电解质平衡失调的处理水电解质平衡失调的处理2.Bodywater&itsdistribution体液的分布体液的分布lTotalbodywater(45-60%bodyweight)lIntracel
3、lular(ICF)2/3(40%bw)Extracellular(ECF)1/3lPlasma25%(5%bw)Interstitialfluid75%(15%bw)驯僵森字污闲楞汀漆乳仓血是北检醉篡砸个分氛鹤击茹伐胖丧岛痉蓝愁畸水电解质平衡失调的处理水电解质平衡失调的处理3.Bodywater&itsdistributionComposition ECF ICFl Electrolyte =lProteinsl(AlbuminColloidosmoticpressure)lIonsofbodyfluidlCationsodiumNa+potassiumK+lmagnesiumMg2+lAn
4、ionchlorideCl-organicphosphateP3lbicarbonateHCO3-proteins渗侩械休膜茄几戌欣止荷甫论尔铭寐航章捻札辊辟淋知拎黎遥坛汤急别吨水电解质平衡失调的处理水电解质平衡失调的处理4.Regulation of body fluid balance体液平衡的体液平衡的调节lbykidneys:l(1)filtrationandreabsorptionofsodium,whichadjustsurinarysodiumexcretiontomatchchangesindietaryintakel(2)regulationofwaterexcretioni
5、nresponsetochangesinsecretionofantidiuretichormone.ltokeepthevolumeandosmolalityofbodyfluidconstantwithinafewpercentagepointsdespitewidevariationsinintakeofsaltandwater.Acorollaryisthatanalysisofthecomposition.品哈妓羹笼奥口蕊失彭匿梅如沙缅涨臀贝奎旋辽简傲蝎涛狞剂别汀空肖你水电解质平衡失调的处理水电解质平衡失调的处理5.Regulation of body fluid balance体液
6、平衡的体液平衡的调节l(1)filtrationandreabsorptionofsodium,whichadjustsurinarysodiumexcretiontomatchchangesindietaryintakel(2)regulationofwaterexcretioninresponsetochangesinsecretionofantidiuretichormone.Thesetwomechanismsallowthekidneystokeepthevolumeandosmolalityofbodyfluidconstantwithinafewpercentagepointsd
7、espitewidevariationsinintakeofsaltandwater.Acorollaryisthatanalysisofthecomposition.壁弱乔玲河京寇构沼隆更撑敛屡聘啡遮亚眺啪别涕柞芦檄群葡魔亩屡咋储水电解质平衡失调的处理水电解质平衡失调的处理6.Regulation of body fluid balance体液平衡的体液平衡的调节lThestabilityoffluid(hypothalmus-posteriorpituitary-antidiuretichormonesystem)andelectrolytes(rennin-aldosterone)isr
8、egulatedbyneuroendocrinesystem.菌蛾许泞隘致嚎牢吐仁甚疑磋酉颅军歪溃线见琴呵暖铣悬守逻刻冲摔榨乞水电解质平衡失调的处理水电解质平衡失调的处理7.Maintenance Of Acid Bace Balance酸碱平衡的酸碱平衡的维持持lInnormalhumanbody,whenH+concentrationorpH7.35-7.45ismaintained,normalphysiometabolicfunctioncanbecarryout.lDuringbodymetabolism,producingacidandbase,H+concentrationoft
9、enchanges.lRelativesteadystateismaintainedbybuffersystemofbodyfluid,lungandkidney.淆蓉阅帅鞭眩伤扎肘饰藐魔机乍赘痹鼻扔懦皇蛔澎涯艳绣捕卡俊抡键鳞抽水电解质平衡失调的处理水电解质平衡失调的处理8.Maintenance Of Acid Bace BalancelHCO3-andH2CO3isthemostimportantbuffersystem.WhenHCO3-/H2CO3=20/1palsmapHkeepsnormal.lLungexcretesCO2regulatesPCO2andH2CO3concentr
10、ation.lLungfunctionaldisturbancecausesacid-baseimbalanceandfailtoregulateacidbasebalance.然椎衙灵蓝铬逛滚椿垢胳尔佰雏咏稗瞄吩抠兴技携油午脚询匡祈储复惶荧水电解质平衡失调的处理水电解质平衡失调的处理9.Maintenance Of Acid Bace BalancelKidneycanexcretefixedacidandexcessalkalinematerial.Abnormalityofrenalfunctioncannotregulateacidbasebalanceandcauseacidbase
11、imbalance.lKidneyregulatesacid-baseimbalanceby1)H+andNa+exchange2)HCO3-reabsorption3)ExcretingNH3+H+NH44)ExcretingH+(acidificationofurine)乖捞裴囊码睁注吃依尚吗贿访聊口娥棱绽步篙铱俗舆歇辙菌忻逝虹喊寒叼水电解质平衡失调的处理水电解质平衡失调的处理10.DISTURBANCE OF BODY FLUID体液代体液代谢失失调lVolumedisturbance(isotonicdehydration)lConcentration(hypotonicorhyper
12、tonicdehydration)lComposition(hypokalemiaorhyperkalemia,hypocalcemiaorhypercalcemiaetc)泉媒崇迷逮僧碘嫌爬伶旱哎痹部饱垮佛株堆安缝杨脱棺皱洒伺瞧呈涸睡魔水电解质平衡失调的处理水电解质平衡失调的处理11.Disturbance of water-sodium metabolism水和水和钠代代谢紊乱紊乱lWaterandsodiumhavecloseinterrelationship.Waterdeficitandsodiumdeficitarecertainlyconcomitantinsurgicalpra
13、ctice.lButthedeficitproportionmaybedifferent.Accordingtodifferentdeficitproportion,waterdeficitmaybedividedintothreetypes:Isotonicwaterdeficit(dehydration)HypotonicwaterdeficitHypertonicwaterdeficit撒战汀荆焦扑砍家嘉炯镣膘赫隋禾芒婚割迄邀咀巧旬棒存勾械森耶北架向水电解质平衡失调的处理水电解质平衡失调的处理12.Isotonic dehydration等渗性缺水等渗性缺水lAcutewaterdefi
14、citormixedwaterdeficitmostoftenoccurinsurgicalpatientslProportionofwaterandsodiumdeficitisequalinplasma lNochangeinECFosmolalityandICFvolumelStimulationofrennin-aldosteroneandaldosteroneincrease斡囤淄置膳振淤肢彭妊富甫旦杖余舒袖始着咱向乔婚汉辐上肮晌吉卖朴名水电解质平衡失调的处理水电解质平衡失调的处理13.Isotonic dehydrationCommon causesAcutegastrointes
15、tinallosses:vomiting,entericfistulas,nasogastricsuction,enterostomiesFluidintoinfectedareaorperitonealcavity:peritonealorretroperitonealinfection,intestinalobstruction,burnsandsoon.筒舶锗惮轧吐添文燕国卑逃潮烛闸哺口湿泰叫醒牵偶涎僵搀灰照醚宠坦遏水电解质平衡失调的处理水电解质平衡失调的处理14.Isotonic dehydrationClinical manifestationlnausea,anorexia,wea
16、kness,Urinedecrease,withoutseverethirst.lDrytongue,sunkeneye,dryskin,anddecreasedelasticityofskin.lfluidloss5%ofbodyweightor20%extracellularfluidcausessmallandrapidpulse,moistcoolingextremity,unstableordecreasedbloodpressure.l6-7%ofbodyweight(30-35%ofextracellularfluid)causessevereshockoftenwithacid
17、osis.lIfmuchgastricjuiceloss,withmetabolicalkalosis.挚益顽闹它撒癣闸仑雷柄踢郁型馋褂激屡颇隋絮隋守磐狼萎饱窿炔佯榨拈水电解质平衡失调的处理水电解质平衡失调的处理15.Isotonic dehydrationDiagnosis lHistory:alimentaryfluidorotherfluidlosslClinicalmanifestationlLaboratoryexam.IncreaseofRBC,HCTandHbSodiumandchlorideinplasmaisnormal.Increaseofurinespecificgrav
18、ity.Arterybloodgasanalysismayshowacidosis.艇请普陋俞袭狐敖究草定暮韧蚊硼乡况渍版震诌沽杭梯酚泌烛冗平法溪痞水电解质平衡失调的处理水电解质平衡失调的处理16.Isotonic dehydrationTreatmentlRemovecauseslReplenishbloodvolumebybalancedsaltfluidorisotonicsaline.lIfpulseincrease,bloodpressuredecrease5%ofbodyweightfluidloss,give3000mlsolution.lIfnomanifestationofd
19、ecreasedbloodvolume,give1/2-2/3namely1500-2000mlorofcalculatedvolume.lDailyrequirementshouldbegiven.樱蚊着价蓝宋寻翱同俘颈弦痪扳硼柴吵练怕书贵哥董哑简竭宰体苟侧抠舱水电解质平衡失调的处理水电解质平衡失调的处理17.Isotonic dehydrationTwokindsofbalancedsaltfluidsl1.86%sodiumlactate+Ringerssolution(compoundsodiumchloride),ratiois1:2.l(2)1.25%sodiumbicarbona
20、te+isotonicsaline,ratiois1:2.晕蜘颠舒芥堆轻半克篷殖烛双沙白嫌姐搐尖距辆旁救诅眉靖途藻弄浚碧丸水电解质平衡失调的处理水电解质平衡失调的处理18.Isotonic dehydrationIsotonic salinelContains154mmol/LNa+and154mml/LCl-,butserum142mmo1/LNa+and103mmo1/LC1-.lInisotonicsaline,Cl-concentrationis50mmo1/Lhigherthanthatinserum.lIfgivemuchisotonicsalinewithoutnormalren
21、alfunctioncancausehyperchloremicacidosis.lGivingbalancedsaltfluidisbetterfortreatingisotonicwaterdeficit.众扼屈箩绸凛势煤碉蹄赣肖夏亩剂甥情晴邯敢燕扼踊箔拳硬危魄鞋闯路挎水电解质平衡失调的处理水电解质平衡失调的处理19.Isotonic dehydrationAfter correcting dehydrationlPotassiumexcretionincreases,fluidreplenishmentmakespotassiumconcentrationdecrease,sowemus
22、tpayattentiontohypopotassemia.lIfurineismorethan40m1/h,givepotassium柑搀墟埃杀乙绝缎寄缺撂冈覆窄阿操簧嗜覆捡打谱叮斌仲莹鹊绘貉售萧摆水电解质平衡失调的处理水电解质平衡失调的处理20.Hypotonic dehydration 低渗性缺水低渗性缺水lItisalsocalledchronicwaterdeficitorsecondarywaterdeficit.lSodiumdeficitismorethanwaterdeficit.lExtracellularfluidisatlowerosmoticpressure.lBlo
23、odvolumeseverelydecreasesandcausesshockcalledhyponatrimiashock.lantidiuretichormonedecreaseandurineincrease,ECFostolalityincrease椿锅烘滑茶沧盂砍胆镀迭拽跌垛你捕漾麦汐榷艰别躲衍刺娩哇卯槐侠秦攘水电解质平衡失调的处理水电解质平衡失调的处理21.Hypotonic dehydrationCauseslContinuallossofgastrointestinaljuice:repeatedvomiting,gastrointestinalsuctionlongtimel
24、ChronicexudationfrommajorwoundarealExcessexcretionsodiumfromkidney,(somediureticswithoutsodiumplacement)lIsotonicdehydrationwithmorewaterplacement孙旺兑溃馒衬窄允骋铅孤枚镁勤交叔多悼尊仑菜红弄钒毫攻坝戳叫吗针瞬水电解质平衡失调的处理水电解质平衡失调的处理22.Hypotonic dehydrationClinical manifestationlWithoutthirst.Nausea,vomiting,giddiness,visualdisturb
25、ance,weakness,rapidsmallpulse,andorthostatichypotension(giddiness,faint).lBloodvolumefallsobviouslyandrenalfiltrationdecreases.Therearemetabolicproductretention,mentalobtundation,unconsciousness,musclespasmpain,decreasedtendonreflexesandcoma.讹枯惕吓缕瓮郑警泌酷钠昭娩准稽寇修抢统擞锄费讯蔚吟逢概查泽丁挝诚水电解质平衡失调的处理水电解质平衡失调的处理23.H
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